منابع مشابه
Procaine in malignant hyperpyrexia.
The caffeine contracture of normal human muscle, which has been used as a model for malignant hyperpyrexia, is greatly potentiated by halothane. Prior administration of procaine markedly reduces the halothane-potentiated caffeine contracture, and procaine given at the height of the contracture induces relaxation. Lignocaine, on the other hand, produces a variable response and sometimes increase...
متن کاملRhabdomyolysis and malignant hyperpyrexia.
detected in any patient by this method. Fourteen patients had raised serum creatine kinase activity (up to 5000 IU/1, normal range < 170 lU/i) and raised serum aspartate transaminase activity (up to 150 IU/1, normal < 35 IU/1). In all cases enzyme activity fell after admission to hospital. Peak serum creatine kinase activity was not significantly related to weight, sex, level of consciousness, ...
متن کاملAn evaluation of procaine in the treatment of malignant hyperpyrexia.
Procaine has been advocated in the treatment of malignant hyperpyrexia, whereas lignocaine has been shown to worsen the condition. Using muscle from patients susceptible to malignant hyperpyrexia in vitro, it has been demonstrated that muscle contracture can occur with procaine on its own, and in one patient the halothane-induced contracture was potentiated by procaine. In other patients the co...
متن کاملMalignant hyperpyrexia: A dread complication
We are, indeed, fortunate in the Anesthesia Department at North Carolina Baptist Hospital to have an excellent supply of equipment. Yet, we are guilty, at times, of failing to take full advantage of it. A prime example is the temperature probe, a valuable aid in the diagnosis of malignant hyperpyrexia. In fact, it is so important that failure to monitor body temperature during anesthesia may ha...
متن کاملIs malignant hyperpyrexia muscle denervated?
To test the hypothesis that human muscular dystrophies may be secondary to denervation, the responses in vitro of muscle in human malignant hyperpyrexia to electrical and pharmacological stimuli have been compared with those of the denervated mouse soleus muscle. The results suggest that the muscle abnormality in malignant hyperpyrexia is different from that produced by denervation. This must c...
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ژورنال
عنوان ژورنال: Survey of Anesthesiology
سال: 1979
ISSN: 0039-6206
DOI: 10.1097/00132586-197902000-00031